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Second, unlike previous NMA studies that reported statistical significance only for indirect outcomes such as laboratory data, this study extensively reviewed studies investigating the effects of GLP-1RA and TZD, the two most promising agents, using invasive and noninvasive technique-based outcomes

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications originally developed for type 2 diabetes management, now increasingly prescribed for weight management

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This adaptability allows the heart to regulate the utilization of different energy substrates according to its needs, maintaining normal cardiac function and ensuring a continuous supply of ATP (34, 50)